STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM77704.1PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: agr:AGROH133_14211 short chain alcohol dehydrogenase-related dehydrogenase. (258 aa)    
Predicted Functional Partners:
AEM79260.1
KEGG: kol:Kole_0163 short-chain dehydrogenase/reductase SDR; manually curated; PFAM: Short-chain dehydrogenase/reductase SDR.
  
  
 
0.921
AEM77705.1
Hypothetical protein.
       0.773
AEM77702.1
PFAM: Phosphotransferase system, galactitol-specific IIC component; KEGG: tte:TTE0183 hypothetical protein.
  
    0.737
AEM77703.1
PFAM: Malate/L-lactate dehydrogenase; KEGG: Malate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family.
  
  
 0.678
AEM78847.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.639
AEM78850.1
KEGG: tbo:Thebr_1317 malonyl CoA-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase.
 
 0.603
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 
 0.583
AEM77706.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; KEGG: thx:Thet_0160 phosphoglycerate dehydrogenase.
  
 
 0.538
AEM79826.1
PFAM: Copper amine oxidase-like, N-terminal; KEGG: slp:Slip_1153 copper amine oxidase domain protein.
   
 0.538
AEM77810.1
PFAM: Glucitol operon activator; KEGG: cbf:CLI_3600 glucitol operon activator protein.
  
  
 0.525
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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