Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77706.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; KEGG: thx:Thet_0160 phosphoglycerate dehydrogenase. (319 aa)    
Predicted Functional Partners:
AEM77707.1
PFAM: SAF domain; KEGG: tbo:Thebr_2122 SAF domain-containing protein.
  
   0.684
AEM77708.1
KEGG: thx:Thet_0162 altronate dehydratase; manually curated; PFAM: D-galactarate dehydratase/Altronate hydrolase, C-terminal.
  
   0.684
AEM77704.1
PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: agr:AGROH133_14211 short chain alcohol dehydrogenase-related dehydrogenase.
   
 
 0.529
AEM77705.1
Hypothetical protein.
       0.509
AEM77709.1
PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal; Mandelate racemase/muconate lactonizing enzyme, N-terminal; KEGG: tbo:Thebr_2120 mandelate racemase/muconate lactonizing protein.
       0.472
AEM77703.1
PFAM: Malate/L-lactate dehydrogenase; KEGG: Malate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family.
     
 0.468
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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