Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM77720.1PFAM: Sugar isomerase (SIS); KEGG: putative phosphosugar isomerase. (387 aa)    
Predicted Functional Partners:
AEM77715.1
PFAM: Phosphotransferase system, sorbose-specific IIC subunit; KEGG: cbe:Cbei_2907 PTS system N-acetylgalactosamine-specific transporter subunit IIC.
 
 
 0.981
AEM77717.1
PFAM: Phosphotransferase system, fructose subfamily IIA component; KEGG: cbe:Cbei_2905 PTS system fructose subfamily IIA component.
 
 
 0.980
AEM77714.1
KEGG: str:Sterm_3399 PTS system, mannose/fructose/sorbose family, IIB subunit; TIGRFAM: Phosphotransferase system, sorbose subfamily IIB component, subgroup; PFAM: Phosphotransferase system, sorbose subfamily IIB component.
 
 
 0.978
AEM77716.1
KEGG: cbe:Cbei_2906 PTS system N-acetylgalactosamine-specific transporter subunit IID; TIGRFAM: Phosphotransferase system, mannose/fructose/sorbose family IID component, subgroup; PFAM: Phosphotransferase system, mannose/fructose/sorbose family IID component.
 
 
 0.978
AEM77719.1
KEGG: cbk:CLL_A3126 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: Carbohydrate/purine kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.978
AEM79454.1
KEGG: cbk:CLL_A3126 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: Carbohydrate/purine kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.930
AEM79456.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: hor:Hore_22680 PfkB domain protein.
  
 
 0.920
AEM77807.1
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
    
 0.904
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.904
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.904
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.