Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77733.1PFAM: GCN5-related N-acetyltransferase; KEGG: tit:Thit_0202 GCN5-related N-acetyltransferase. (322 aa)    
Predicted Functional Partners:
AEM77732.1
PFAM: Glycoside hydrolase, family 3, N-terminal; Glycoside hydrolase, family 3, C-terminal; KEGG: tit:Thit_0201 glycoside hydrolase family 3 domain protein.
    0.879
AEM77734.1
KEGG: tit:Thit_0203 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase 1.
       0.668
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.564
tlp
KEGG: tbo:Thebr_1998 small, acid-soluble spore protein tlp; TIGRFAM: Small acid-soluble spore protein, thioredoxin-like; HAMAP: Small, acid-soluble spore protein tlp; Belongs to the Tlp family.
  
     0.551
AEM77598.1
KEGG: tbo:Thebr_2215 phage SPO1 DNA polymerase-like protein; TIGRFAM: Phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase-like.
  
    0.537
AEM78710.1
KEGG: tbo:Thebr_1170 hypothetical protein.
     
 0.515
cinA
KEGG: tbo:Thebr_1221 competence/damage-inducible protein CinA; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; Belongs to the CinA family.
  
  
 0.466
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
     
 0.463
sigI
RNA polymerase sigma-I factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily.
  
  
 0.455
ribBA
GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.448
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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