Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77755.1KEGG: tmt:Tmath_0302 efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Biotin/lipoyl attachment. (603 aa)    
Predicted Functional Partners:
AEM77757.1
PFAM: Protein of unknown function DUF214, permase predicted; KEGG: tbo:Thebr_2062 hypothetical protein.
 
 
 0.995
AEM78597.1
PFAM: Protein of unknown function DUF214, permase predicted; KEGG: tte:TTE1198 ABC-type transport systems, involved in lipoprotein release, permease components.
 
 
 0.978
macB
ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.968
AEM78598.1
KEGG: tbo:Thebr_1058 ABC transporter-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
 
 
 0.858
AEM77754.1
KEGG: tbo:Thebr_2065 MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; PFAM: Multi antimicrobial extrusion protein MatE.
     
 0.564
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.538
AEM77752.1
tRNA/rRNA methyltransferase (SpoU); Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.506
AEM77758.1
Fumarylacetoacetate (FAA) hydrolase; PFAM: Fumarylacetoacetase, C-terminal-like; KEGG: tbo:Thebr_2061 5-carboxymethyl-2-hydroxymuconate delta-isomerase.
       0.425
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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