Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM77757.1PFAM: Protein of unknown function DUF214, permase predicted; KEGG: tbo:Thebr_2062 hypothetical protein. (391 aa)    
Predicted Functional Partners:
macB
ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 0.998
AEM77755.1
KEGG: tmt:Tmath_0302 efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Biotin/lipoyl attachment.
 
 
 0.995
AEM78598.1
KEGG: tbo:Thebr_1058 ABC transporter-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
 
 0.994
AEM78552.1
KEGG: cow:Calow_1350 ABC transporter-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
 
 0.968
AEM78599.1
Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; KEGG: tbo:Thebr_1059 RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.886
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
    
 0.832
AEM79272.1
PFAM: Secretion protein HlyD; KEGG: ttm:Tthe_0336 secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.796
AEM78046.1
KEGG: tbo:Thebr_1808 ABC transporter-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
 
 
    0.728
metN
ABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
      0.700
AEM77897.1
KEGG: tbo:Thebr_1972 ABC transporter-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
 
    0.698
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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