STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM77760.1PFAM: Sodium/calcium exchanger membrane region; KEGG: tte:TTE0262 Ca2+/Na+ antiporter. (331 aa)    
Predicted Functional Partners:
AEM78004.1
KEGG: tbo:Thebr_1846 hypothetical protein.
  
    0.566
AEM77759.1
PFAM: Protein of unknown function DUF1646; KEGG: tte:TTE0261 hypothetical protein.
 
     0.550
AEM79553.1
PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; KEGG: tbo:Thebr_0455 MazG nucleotide pyrophosphohydrolase.
 
     0.449
AEM77761.1
Protein of unknown function UPF0236; KEGG: tbo:Thebr_1708 hypothetical protein; manually curated; PFAM: Uncharacterised protein family UPF0236.
       0.409
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.406
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.