Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM77761.1Protein of unknown function UPF0236; KEGG: tbo:Thebr_1708 hypothetical protein; manually curated; PFAM: Uncharacterised protein family UPF0236. (476 aa)    
Predicted Functional Partners:
AEM78875.1
KEGG: tbo:Thebr_1342 serine/threonine-protein kinase-like domain-containing protein; PFAM: Serine/threonine-protein kinase-like domain; PASTA; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, subgroup, catalytic domain; PASTA.
  
 
 0.697
AEM77759.1
PFAM: Protein of unknown function DUF1646; KEGG: tte:TTE0261 hypothetical protein.
 
     0.571
AEM77765.1
Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein.
   
   0.563
AEM78215.1
KEGG: ttm:Tthe_2548 hypothetical protein.
  
     0.522
AEM78035.1
KEGG: tte:TTE0501 cell wall biosynthesis glycosyltransferase; PFAM: Glycosyl transferase, group 1; Glycosyl transferase, family 2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat.
  
 
   0.519
AEM78878.1
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.518
addB
ATP-dependent helicase/deoxyribonuclease subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily.
       0.500
addA
ATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase.
       0.500
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
   0.495
AEM77566.1
PFAM: Protein of unknown function DUF1646; KEGG: tte:TTE2541 hypothetical protein.
  
     0.466
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.