STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM77768.1Ferric uptake regulator, Fur family; PFAM: Ferric-uptake regulator; KEGG: tbo:Thebr_2054 ferric-uptake regulator; Belongs to the Fur family. (144 aa)    
Predicted Functional Partners:
AEM77767.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.861
AEM77769.1
KEGG: tbo:Thebr_2053 hypothetical protein.
 
    0.855
AEM79215.1
Ferric uptake regulator, Fur family; PFAM: Ferric-uptake regulator; KEGG: tit:Thit_1662 ferric uptake regulator, Fur family; Belongs to the Fur family.
  
     0.741
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.541
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.505
AEM77770.1
Protein of unknown function UPF0236; PFAM: Uncharacterised protein family UPF0236; KEGG: tte:TTE2708 hypothetical protein.
       0.487
AEM79810.1
KEGG: thx:Thet_1759 hypothetical protein.
 
    0.486
AEM77766.1
PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: thx:Thet_0246 aromatic amino acid beta-eliminating lyase/threonine aldolase.
       0.484
AEM78570.1
KEGG: tbo:Thebr_1031 CoA-binding domain-containing protein; manually curated; PFAM: CoA-binding.
  
    0.459
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.420
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.