STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (311 aa)    
Predicted Functional Partners:
AEM77965.1
KEGG: tbo:Thebr_1890 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
 
 0.992
AEM79696.1
KEGG: tmt:Tmath_2023 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
 
 0.992
AEM79177.1
KEGG: thx:Thet_1715 pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region.
  
 0.990
AEM79642.1
PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; KEGG: tbo:Thebr_0347 malic protein NAD-binding protein.
  
 0.954
AEM78718.1
PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Transketolase, C-terminal; KEGG: tbo:Thebr_1178 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.949
AEM79531.1
PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Transketolase, C-terminal; KEGG: thx:Thet_1975 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.949
AEM78746.1
PFAM: Aminotransferase, class I/II; KEGG: tbo:Thebr_1213 class I/II aminotransferase.
  
 0.940
AEM78494.1
KEGG: tbo:Thebr_1386 pyruvate, phosphate dikinase; TIGRFAM: Pyruvate, phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; PEP-utilising enzyme; Belongs to the PEP-utilizing enzyme family.
  
 
 0.935
AEM78713.1
PFAM: Conserved carboxylase region; Pyruvate carboxyltransferase; KEGG: tbo:Thebr_1173 conserved carboxylase region.
    
 0.928
AEM78719.1
PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: tbo:Thebr_1179 thiamine pyrophosphate TPP-binding domain-containing protein.
  
 
 0.926
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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