STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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[Homology]
Score
AEM77807.1Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (302 aa)    
Predicted Functional Partners:
AEM79177.1
KEGG: thx:Thet_1715 pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region.
 
 
 0.990
pgi
KEGG: tbo:Thebr_0713 glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 0.975
AEM77806.1
KEGG: hor:Hore_18020 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: Ketose-bisphosphate aldolase, class-II; PFAM: Ketose-bisphosphate aldolase, class-II.
  
 
 0.974
AEM77804.1
Transketolase domain-containing protein; PFAM: Transketolase, N-terminal; KEGG: tbo:Thebr_0504 transketolase domain-containing protein.
    
  0.952
AEM77805.1
Transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: thx:Thet_1947 transketolase central region.
    
  0.952
AEM77657.1
KEGG: tbo:Thebr_2162 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class II; Ketose-bisphosphate aldolase, class-II; PFAM: Ketose-bisphosphate aldolase, class-II.
  
 
 0.921
AEM77718.1
KEGG: fructose-bisphosphate aldolase; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class II; Ketose-bisphosphate aldolase, class-II; PFAM: Ketose-bisphosphate aldolase, class-II.
  
 
 0.921
AEM79128.1
KEGG: thx:Thet_1016 ketose-bisphosphate aldolase; TIGRFAM: Ketose-bisphosphate aldolase, class-II; PFAM: Ketose-bisphosphate aldolase, class-II.
  
 
 0.921
AEM79455.1
KEGG: fructose-bisphosphate aldolase; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class II; Ketose-bisphosphate aldolase, class-II; PFAM: Ketose-bisphosphate aldolase, class-II.
  
 
 0.921
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
  
0.918
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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