Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77835.1PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: thx:Thet_0290 TetR family transcriptional regulator. (194 aa)    
Predicted Functional Partners:
AEM77836.1
KEGG: thx:Thet_0291 hypothetical protein; manually curated; PFAM: Protein of unknown function DUF2229, CoA enzyme activase.
       0.623
AEM77837.1
KEGG: tbo:Thebr_2009 hypothetical protein.
       0.623
AEM77838.1
KEGG: tmt:Tmath_0356 CoA-substrate-specific enzyme activase; TIGRFAM: CoA enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type.
       0.622
AEM77839.1
Cation diffusion facilitator family transporter; KEGG: tko:TK2009 cobalt/zinc/cadmium cation efflux pump protein; TIGRFAM: Cation efflux protein; PFAM: Cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
     
 0.597
AEM77834.1
PFAM: NADPH-dependent FMN reductase; KEGG: mvu:Metvu_0192 NADPH-dependent FMN reductase.
     
 0.572
pth
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.447
AEM79712.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: tbo:Thebr_0292 EAL domain-containing protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted.
  
   
 0.436
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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