Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77839.1Cation diffusion facilitator family transporter; KEGG: tko:TK2009 cobalt/zinc/cadmium cation efflux pump protein; TIGRFAM: Cation efflux protein; PFAM: Cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (300 aa)    
Predicted Functional Partners:
AEM77836.1
KEGG: thx:Thet_0291 hypothetical protein; manually curated; PFAM: Protein of unknown function DUF2229, CoA enzyme activase.
       0.726
AEM77837.1
KEGG: tbo:Thebr_2009 hypothetical protein.
       0.726
AEM77838.1
KEGG: tmt:Tmath_0356 CoA-substrate-specific enzyme activase; TIGRFAM: CoA enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type.
       0.726
AEM77835.1
PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: thx:Thet_0290 TetR family transcriptional regulator.
     
 0.597
AEM79204.1
Copper-translocating P-type ATPase; KEGG: tte:TTE2463 cation transport ATPase; TIGRFAM: ATPase, P type, cation/copper-transporter; Copper ion-binding; ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase.
 
  
 0.544
polA
5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
    0.495
AEM79209.1
KEGG: tit:Thit_1657 copper ion binding protein; TIGRFAM: Copper ion-binding; PFAM: Heavy metal transport/detoxification protein.
     
 0.459
AEM77664.1
PFAM: Zinc/iron permease; KEGG: thx:Thet_0130 zinc/iron permease.
  
 0.431
AEM77834.1
PFAM: NADPH-dependent FMN reductase; KEGG: mvu:Metvu_0192 NADPH-dependent FMN reductase.
       0.417
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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