Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77861.1PFAM: Malate/L-lactate dehydrogenase; KEGG: Malate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (340 aa)    
Predicted Functional Partners:
AEM77860.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; KEGG: abi:Aboo_1421 phosphoglycerate dehydrogenase.
  
  
 0.741
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.554
AEM77862.1
PFAM: Phosphotransferase system, lactose/cellobiose-specific IIA subunit; KEGG: tte:TTE0336 phosphotransferase system cellobiose-specific component IIA.
       0.444
AEM77858.1
PFAM: Sugar isomerase (SIS); KEGG: tvo:TVN0825 glucosamine 6-phosphate synthase.
  
    0.406
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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