Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77873.1KEGG: tbo:Thebr_0881 molybdenum cofactor synthesis domain-containing protein; TIGRFAM: Molybdenum cofactor synthesis; PFAM: Molybdopterin binding. (165 aa)    
Predicted Functional Partners:
AEM77874.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 0.999
AEM77875.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 0.999
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 0.999
AEM77878.1
MOSC domain containing protein; PFAM: Molybdenum cofactor sulfurase, C-terminal; KEGG: tbo:Thebr_0886 MOSC domain-containing protein.
   
 0.994
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.973
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
 
      0.752
AEM77871.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; KEGG: thx:Thet_1514 binding-protein-dependent transport systems inner membrane component.
 
   
 0.632
AEM77867.1
PFAM: ThiamineS; KEGG: tbo:Thebr_0874 thiamineS protein.
  
  
 0.578
AEM77869.1
KEGG: tbo:Thebr_0877 molybdopterin-guanine dinucleotide biosynthesis protein B; TIGRFAM: Molybdopterin-guanine dinucleotide biosynthesis MobB region; PFAM: Molybdopterin-guanine dinucleotide biosynthesis MobB region; Putative Fe-S cluster.
 
 
 
 0.539
AEM77872.1
KEGG: tbo:Thebr_0880 ABC transporter-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
     
 0.481
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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