STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtlDMannitol-1-phosphate 5-dehydrogenase; KEGG: thx:Thet_0313 mannitol dehydrogenase domain-containing protein; HAMAP: Mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal. (388 aa)    
Predicted Functional Partners:
AEM77879.1
KEGG: thx:Thet_0310 PTS system, mannitol-specific IIC subunit; TIGRFAM: Phosphotransferase system, mannitol-specific enzyme IIC; PFAM: Phosphotransferase system, lactose/cellobiose-specific IIB subunit; Phosphotransferase system, EIIC.
 
 
 0.999
AEM77881.1
PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; KEGG: tbo:Thebr_1987 phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.
 
 0.999
AEM77880.1
Transcriptional antiterminator, BglG; PFAM: PRD; Phosphotransferase system, lactose/cellobiose-specific IIB subunit; KEGG: tbo:Thebr_1988 protein-N(pi)-phosphohistidine--sugar phosphotransferase.
  
 0.972
AEM79648.1
PTS modulated transcriptional regulator, MtlR family; PFAM: PRD; Helix-turn-helix, type 11; Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; KEGG: tbo:Thebr_0341 protein-N(pi)-phosphohistidine--sugar phosphotransferase.
  
 0.950
AEM77808.1
PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: cbk:CLL_A0401 sorbitol-6-phosphate 2-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.943
AEM79242.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: thx:Thet_1794 PfkB domain-containing protein.
    
 0.918
AEM79077.1
KEGG: tbo:Thebr_0765 mannose-6-phosphate isomerase, class I; TIGRFAM: Mannose-6-phosphate isomerase, type I; PFAM: Mannose-6-phosphate isomerase, type I.
    
 0.911
AEM77807.1
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
    
 0.910
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.910
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.910
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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