Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77904.1PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; KEGG: tbo:Thebr_1965 LysR substrate-binding protein. (294 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.708
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.687
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.676
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.656
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.614
AEM79712.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: tbo:Thebr_0292 EAL domain-containing protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted.
  
  
 0.513
AEM78502.1
Transcriptional regulator, Crp/Fnr family; KEGG: tbo:Thebr_0983 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SMART: HTH transcriptional regulator, Crp.
   
 
 0.441
AEM79173.1
Transcriptional regulator, Crp/Fnr family; KEGG: tbo:Thebr_0706 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SMART: HTH transcriptional regulator, Crp.
   
 
 0.441
AEM80012.1
KEGG: tmt:Tmath_2258 transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SMART: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp.
   
 
 0.441
polA
5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
      
 0.425
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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