Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM77920.1KEGG: thx:Thet_1006 hypothetical protein. (161 aa)    
Predicted Functional Partners:
AEM77921.1
KEGG: thx:Thet_1007 hypothetical protein.
 
     0.961
AEM77923.1
Cobalbumin biosynthesis protein; PFAM: Cobinamide kinase/cobinamide phosphate guanyltransferase; KEGG: thx:Thet_0348 adenosylcobinamide-phosphate guanylyltransferase.
 
     0.807
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
     0.772
AEM77922.1
KEGG: tbo:Thebr_1944 L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/II.
       0.717
AEM77925.1
PFAM: Cobalamin (vitamin B12) biosynthesis CbiX; KEGG: tit:Thit_0350 cobalamin (vitamin B12) biosynthesis CbiX protein.
       0.625
AEM79028.1
KEGG: thx:Thet_0909 hypothetical protein.
  
     0.520
ribBA
GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
  
 0.476
AEM77537.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
      
 0.439
AEM78708.1
PFAM: Glucose-inhibited division protein A-related; KEGG: tbo:Thebr_1168 glucose-inhibited division protein A.
  
     0.425
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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