Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77966.1KEGG: tbo:Thebr_1888 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region. (199 aa)    
Predicted Functional Partners:
AEM79649.1
Diguanylate cyclase with GAF sensor; TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; GAF; KEGG: tbo:Thebr_0340 diguanylate cyclase; SMART: Diguanylate cyclase, predicted; GAF.
 
 0.820
AEM79731.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; KEGG: tte:TTE1052 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate cyclase, predicted.
 
 
 0.819
AEM79712.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: tbo:Thebr_0292 EAL domain-containing protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted.
 
  
 0.725
AEM78162.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS fold-3; PAS fold; KEGG: tte:TTE1081 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS; PAC motif.
  
 0.616
AEM79709.1
Response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; SMART: Signal transduction response regulator, receiver region; PAS; PAC motif; manually curated; KEGG: tit:Thit_0615 response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS; PFAM: PAS fold; Signal transduction response regulator, receiver region; Diguanylate cyclase, predicted.
   
 0.548
AEM79212.1
TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate cyclase, predicted; PAS fold; Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: thx:Thet_1766 diguanylate cyclase and metal dependent phosphohydrolase; SMART: Diguanylate cyclase, predicted; PAS; PAC motif.
 
   
 0.547
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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