STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM77967.1KEGG: thx:Thet_0436 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache, type 2; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain. (587 aa)    
Predicted Functional Partners:
AEM78734.1
MCP methyltransferase, CheR-type; KEGG: tbo:Thebr_1201 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase, CheR-type; SMART: MCP methyltransferase, CheR-type.
 
 0.983
AEM78795.1
CheB methylesterase; PFAM: Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; KEGG: tbo:Thebr_1262 protein-glutamate methylesterase.
 
 0.983
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.983
AEM79560.1
MCP methyltransferase, CheR-type; KEGG: tte:TTE1037 methylase of chemotaxis methyl-accepting proteins; PFAM: MCP methyltransferase, CheR-type; SMART: MCP methyltransferase, CheR-type.
 
 0.982
AEM78575.1
CheW protein; KEGG: tbo:Thebr_1036 CheW domain-containing protein; PFAM: CheW-like protein; SMART: CheW-like protein.
 
 0.981
AEM78793.1
CheW protein; KEGG: tbo:Thebr_1260 CheW domain-containing protein; PFAM: CheW-like protein; SMART: CheW-like protein.
 
 0.981
AEM78794.1
KEGG: thx:Thet_1232 CheA signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, P2 response regulator-binding; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup, homodimeric; ATP-binding region, ATPase-like; CheW-like protein; SMART: CheW-like protein; Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPase-like.
 
 0.981
AEM79557.1
Hpt protein; KEGG: hor:Hore_07600 CheA signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, P2 response regulator-binding; SMART: Signal transduction histidine kinase, phosphotransfer (Hpt) region.
 
 0.981
AEM79558.1
Putative CheA signal transduction histidine kinase; KEGG: tte:TTE1039 chemotaxis protein histidine kinase-like kinase; PFAM: CheW-like protein; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup, homodimeric; SMART: ATP-binding region, ATPase-like; CheW-like protein.
 
 0.981
cheD
CheD, stimulates methylation of MCP proteins; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.978
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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