STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
csrACarbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (75 aa)    
Predicted Functional Partners:
fliW
Flagellar assembly factor fliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.999
flgK
KEGG: tbo:Thebr_1829 flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal.
 
  
 0.897
AEM78023.1
KEGG: tbo:Thebr_1828 flagellar hook-associated protein 3; TIGRFAM: Flagellar hook-associated protein 3; PFAM: Flagellin, N-terminal; Flagellin, C-terminal.
 
  
 0.897
AEM78020.1
PFAM: Anti-sigma-28 factor, FlgM; KEGG: tbo:Thebr_1831 anti-sigma-28 factor FlgM family protein.
  
  
 0.847
AEM78040.1
KEGG: tbo:Thebr_1815 flagellar protein FliS; manually curated; PFAM: Flagellar protein FliS.
 
  
 0.835
AEM78024.1
KEGG: tbo:Thebr_1827 hypothetical protein.
  
    0.834
AEM78027.1
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
  
 0.821
AEM78021.1
Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1830 FlgN family protein.
  
    0.768
hfq
Protein hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
  
 0.746
AEM78806.1
CheC, inhibitor of MCP methylation / FliN fusion protein; KEGG: tbo:Thebr_1273 flagellar motor switch protein FliN; TIGRFAM: Flagellar motor switch FliN; PFAM: Surface presentation of antigen (SpoA); CheC-like protein.
 
   0.730
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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