Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM78052.1KEGG: thx:Thet_0526 hypothetical protein. (166 aa)    
Predicted Functional Partners:
AEM78051.1
3H domain-containing protein; PFAM: 3H domain; Helix-turn-helix, type 11; KEGG: thx:Thet_0525 3H domain-containing protein.
 
   
 0.717
AEM79340.1
PFAM: Lipoprotein LpqB, GerMN domain; KEGG: tte:TTE1070 hypothetical protein.
  
     0.659
AEM78049.1
TIGRFAM: HDIG; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: tit:Thit_0514 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD region.
       0.512
AEM78050.1
KEGG: thx:Thet_0524 hypothetical protein.
       0.512
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
      
 0.410
AEM77590.1
Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2222 D-alanine--D-alanine ligase.
 
     0.404
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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