Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78077.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; KEGG: tte:TTE0548 3-hydroxybutyryl-CoA dehydrogenase. (281 aa)    
Predicted Functional Partners:
AEM78072.1
Enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; KEGG: tte:TTE0544 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.999
AEM78079.1
TIGRFAM: Thiolase; KEGG: tte:TTE0549 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 0.999
AEM78073.1
PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central region; KEGG: tte:TTE0545 acyl-CoA dehydrogenase.
 0.989
AEM78075.1
PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; Electron transfer flavoprotein, alpha subunit, C-terminal; KEGG: tte:TTE0547 electron transfer flavoprotein subunit alpha.
  
 
 0.900
AEM78074.1
PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; KEGG: tte:TTE0546 electron transfer flavoprotein subunit beta.
  
 
 0.875
AEM79860.1
PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase; KEGG: thx:Thet_2299 iron-containing alcohol dehydrogenase.
  
 0.696
rex
Redox-sensing transcriptional repressor rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
     
 0.677
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.675
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.561
AEM78089.1
PFAM: Acetyl-CoA hydrolase/transferase; KEGG: tte:TTE0554 acetyl-CoA hydrolase.
     
 0.558
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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