Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEM78096.1Two component transcriptional regulator, LytTR family; KEGG: tbo:Thebr_1779 LytTr DNA-binding region; PFAM: LytTr DNA-binding region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region. (236 aa)    
Predicted Functional Partners:
AEM78387.1
KEGG: tte:TTE0871 regulator of cell autolysis; PFAM: Signal transduction histidine kinase, internal region; Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like.
 
 
 0.852
AEM78097.1
KEGG: thx:Thet_0549 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like.
 
  
 0.823
AEM78098.1
KEGG: thx:Thet_0550 accessory gene regulator B; PFAM: Accessory gene regulator B; SMART: Accessory gene regulator B.
     
 0.770
AEM78095.1
KEGG: tbo:Thebr_1780 hypothetical protein.
       0.715
AEM77786.1
KEGG: thx:Thet_0264 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SMART: HAMP linker domain; ATP-binding region, ATPase-like.
 
  
 0.605
AEM77976.1
KEGG: thx:Thet_0445 multi-sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; Cache; ATP-binding region, ATPase-like; SMART: HAMP linker domain.
 
  
 0.601
AEM79681.1
KEGG: thx:Thet_2123 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS.
 
   
 0.501
AEM78312.1
KEGG: thx:Thet_0719 winged helix family two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region.
  
   
 0.492
AEM79801.1
Two component transcriptional regulator, winged helix family; KEGG: ere:EUBREC_1613 response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region.
  
   
 0.491
AEM78311.1
Manually curated; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; KEGG: tbo:Thebr_1572 ATP-binding region ATPase domain-containing protein; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain.
  
   
 0.486
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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