Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78097.1KEGG: thx:Thet_0549 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like. (287 aa)    
Predicted Functional Partners:
AEM78096.1
Two component transcriptional regulator, LytTR family; KEGG: tbo:Thebr_1779 LytTr DNA-binding region; PFAM: LytTr DNA-binding region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
 
  
 0.823
AEM78098.1
KEGG: thx:Thet_0550 accessory gene regulator B; PFAM: Accessory gene regulator B; SMART: Accessory gene regulator B.
       0.802
AEM78095.1
KEGG: tbo:Thebr_1780 hypothetical protein.
       0.665
AEM79038.1
KEGG: tbo:Thebr_0806 hypothetical protein.
  
     0.437
AEM77680.1
S-layer domain-containing protein; PFAM: S-layer homology region; KEGG: tte:TTE0166 S-layer-like domain-containing protein.
  
     0.435
buk
TIGRFAM: Butyrate kinase; HAMAP: butyrate kinase; KEGG: tbo:Thebr_0474 butyrate kinase; PFAM: Acetate/butyrate kinase; Belongs to the acetokinase family.
       0.431
AEM78099.1
KEGG: tbo:Thebr_1776 hypothetical protein.
       0.421
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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