Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
AEM78103.1KEGG: tbo:Thebr_1771 8-oxoguanine DNA glycosylase domain-containing protein; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; SMART: HhH-GPD domain. (297 aa)    
Predicted Functional Partners:
AEM78104.1
PFAM: Protein of unknown function DUF554; KEGG: tbo:Thebr_1770 hypothetical protein.
       0.822
AEM78105.1
KEGG: tbo:Thebr_1769 hypothetical protein.
       0.767
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.722
AEM79062.1
KEGG: tbo:Thebr_0784 hypothetical protein.
  
     0.707
AEM79555.1
Exodeoxyribonuclease III Xth; KEGG: tte:TTE2226 exonuclease III; TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; PFAM: Endonuclease/exonuclease/phosphatase.
   
 0.707
AEM78648.1
KEGG: tbo:Thebr_1108 xylose isomerase domain-containing protein; PFAM: Xylose isomerase, TIM barrel domain; SMART: Endodeoxyribonuclease IV.
   
 
 0.699
polA
5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.673
AEM78323.1
KEGG: tbo:Thebr_1561 hypothetical protein.
  
     0.611
AEM79978.1
KEGG: thx:Thet_2395 AAA ATPase; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core.
  
     0.607
AEM78100.1
KEGG: tbo:Thebr_1775 hypothetical protein.
       0.534
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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