Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78136.1KEGG: tbo:Thebr_1743 biotin and thiamin synthesis associated; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (466 aa)    
Predicted Functional Partners:
AEM79799.1
TIGRFAM: Small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; KEGG: tit:Thit_2142 small GTP-binding protein; SMART: Ras small GTPase, Ras type.
  
 0.967
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.926
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.905
AEM78409.1
KEGG: tbo:Thebr_1491 hydrogenase, Fe-only; TIGRFAM: Iron hydrogenase, subset; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Iron hydrogenase, small subunit-like.
 
   
 0.867
AEM79807.1
PFAM: ThiamineS; KEGG: tte:TTE2469 hypothetical protein.
  
  
 0.816
AEM78947.1
KEGG: tbo:Thebr_0898 hypothetical protein.
 
     0.812
AEM78822.1
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.804
AEM79734.1
PFAM: Sulphate transporter/antisigma-factor antagonist STAS; KEGG: tte:TTE1048 STAS domain-containing protein.
  
    0.756
AEM79735.1
PFAM: Sulphate transporter/antisigma-factor antagonist STAS; KEGG: tte:TTE1047 STAS domain-containing protein.
  
    0.756
AEM79346.1
PFAM: Sporulation stage II, protein E C-terminal; KEGG: tte:TTE0698 hypothetical protein.
  
    0.726
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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