Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM78137.1PTS modulated transcriptional regulator, MtlR family; PFAM: PRD; Helix-turn-helix, type 11; Phosphotransferase system, lactose/cellobiose-specific IIB subunit; KEGG: tbo:Thebr_1742 protein-N(pi)-phosphohistidine--sugar phosphotransferase. (693 aa)    
Predicted Functional Partners:
AEM78139.1
PFAM: Phosphotransferase system, lactose/cellobiose-specific IIB subunit; KEGG: tbo:Thebr_1740 phosphotransferase system lactose/cellobiose-specific IIB subunit.
 
  
 0.900
AEM77879.1
KEGG: thx:Thet_0310 PTS system, mannitol-specific IIC subunit; TIGRFAM: Phosphotransferase system, mannitol-specific enzyme IIC; PFAM: Phosphotransferase system, lactose/cellobiose-specific IIB subunit; Phosphotransferase system, EIIC.
 
  
 0.899
AEM78140.1
PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
  
 0.895
AEM78141.1
PFAM: Phosphotransferase system, lactose/cellobiose-specific IIA subunit; KEGG: tbo:Thebr_1738 phosphotransferase system PTS lactose/cellobiose-specific IIA subunit.
 
  
 0.877
mtlD
Mannitol-1-phosphate 5-dehydrogenase; KEGG: thx:Thet_0313 mannitol dehydrogenase domain-containing protein; HAMAP: Mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal.
  
 0.862
AEM77881.1
PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; KEGG: tbo:Thebr_1987 phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.
 
  
 0.772
AEM79645.1
KEGG: tbo:Thebr_0344 PTS system, fructose-specific transporter subunit IIB; TIGRFAM: Phosphotransferase system, fructose-specific IIB subunit; PFAM: Phosphotransferase system, fructose-specific IIB subunit.
  
  
 0.761
AEM79646.1
KEGG: tpd:Teth39_0333 PTS system, fructose subfamily, IIC subunit; TIGRFAM: Phosphotransferase system, fructose IIC component; PFAM: Phosphotransferase system, EIIC.
  
  
 0.761
AEM79910.1
KEGG: tbo:Thebr_0159 PTS system, fructose subfamily, IIC subunit; TIGRFAM: Phosphotransferase system, fructose IIC component; Phosphotransferase system, fructose-specific IIB subunit; PFAM: Phosphotransferase system, fructose-specific IIB subunit; Phosphotransferase system, EIIC.
  
  
 0.761
AEM77989.1
KEGG: tbo:Thebr_1870 PTS system, N-acetylglucosamine-specific IIBC subunit; TIGRFAM: Phosphotransferase system, N-acetylglucosamine-specific IIBC component; Phosphotransferase system, glucose-like IIB component; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site.
  
 
 0.760
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.