| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEM77681.1 | AEM78160.1 | Thewi_0172 | Thewi_0707 | S-layer domain-containing protein; PFAM: S-layer homology region; KEGG: tte:TTE0167 S-layer-like domain-containing protein. | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | 0.409 |
| AEM78157.1 | AEM78159.1 | Thewi_0704 | Thewi_0706 | Cell wall hydrolase/autolysin; KEGG: tit:Thit_0595 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; Copper amine oxidase-like, N-terminal; SMART: Cell wall hydrolase/autolysin, catalytic. | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.513 |
| AEM78157.1 | AEM78160.1 | Thewi_0704 | Thewi_0707 | Cell wall hydrolase/autolysin; KEGG: tit:Thit_0595 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; Copper amine oxidase-like, N-terminal; SMART: Cell wall hydrolase/autolysin, catalytic. | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | 0.520 |
| AEM78157.1 | rph | Thewi_0704 | Thewi_0705 | Cell wall hydrolase/autolysin; KEGG: tit:Thit_0595 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; Copper amine oxidase-like, N-terminal; SMART: Cell wall hydrolase/autolysin, catalytic. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.513 |
| AEM78159.1 | AEM78157.1 | Thewi_0706 | Thewi_0704 | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Cell wall hydrolase/autolysin; KEGG: tit:Thit_0595 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; Copper amine oxidase-like, N-terminal; SMART: Cell wall hydrolase/autolysin, catalytic. | 0.513 |
| AEM78159.1 | AEM78160.1 | Thewi_0706 | Thewi_0707 | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | 0.924 |
| AEM78159.1 | rph | Thewi_0706 | Thewi_0705 | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.991 |
| AEM78160.1 | AEM77681.1 | Thewi_0707 | Thewi_0172 | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | S-layer domain-containing protein; PFAM: S-layer homology region; KEGG: tte:TTE0167 S-layer-like domain-containing protein. | 0.409 |
| AEM78160.1 | AEM78157.1 | Thewi_0707 | Thewi_0704 | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | Cell wall hydrolase/autolysin; KEGG: tit:Thit_0595 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; Copper amine oxidase-like, N-terminal; SMART: Cell wall hydrolase/autolysin, catalytic. | 0.520 |
| AEM78160.1 | AEM78159.1 | Thewi_0707 | Thewi_0706 | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.924 |
| AEM78160.1 | AEM79640.1 | Thewi_0707 | Thewi_2292 | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | Transcriptional repressor, CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes; KEGG: tbo:Thebr_0349 Firmicute transcriptional repressor of class III stress genes; Belongs to the CtsR family. | 0.446 |
| AEM78160.1 | birA | Thewi_0707 | Thewi_1937 | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.416 |
| AEM78160.1 | rph | Thewi_0707 | Thewi_0705 | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.851 |
| AEM79640.1 | AEM78160.1 | Thewi_2292 | Thewi_0707 | Transcriptional repressor, CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes; KEGG: tbo:Thebr_0349 Firmicute transcriptional repressor of class III stress genes; Belongs to the CtsR family. | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | 0.446 |
| birA | AEM78160.1 | Thewi_1937 | Thewi_0707 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | 0.416 |
| birA | rph | Thewi_1937 | Thewi_0705 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.456 |
| rph | AEM78157.1 | Thewi_0705 | Thewi_0704 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Cell wall hydrolase/autolysin; KEGG: tit:Thit_0595 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; Copper amine oxidase-like, N-terminal; SMART: Cell wall hydrolase/autolysin, catalytic. | 0.513 |
| rph | AEM78159.1 | Thewi_0705 | Thewi_0706 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.991 |
| rph | AEM78160.1 | Thewi_0705 | Thewi_0707 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Phosphodiesterase, MJ0936 family; KEGG: tbo:Thebr_1722 phosphodiesterase; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. | 0.851 |
| rph | birA | Thewi_0705 | Thewi_1937 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.456 |
