Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
AEM78234.1KEGG: pca:Pcar_0790 hypothetical protein. (136 aa)    
Predicted Functional Partners:
AEM79959.1
KEGG: tbo:Thebr_0120 glutaredoxin-like protein, YruB-family; TIGRFAM: Glutaredoxin-like protein, YruB; PFAM: Glutaredoxin.
  
  
 0.788
AEM78235.1
Hypothetical protein.
       0.760
AEM78233.1
Hypothetical protein.
       0.750
AEM79191.1
PFAM: Bacterial extracellular solute-binding, family 1; KEGG: thx:Thet_1729 extracellular solute-binding protein family 1.
    
 
 0.742
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
   
 
 0.705
AEM78237.1
PFAM: Plasmid pRiA4b ORF-3-like; KEGG: thx:Thet_0660 plasmid pRiA4b ORF-3 family protein.
   
 
 0.705
AEM78257.1
KEGG: thx:Thet_0673 hypothetical protein.
   
 
 0.705
AEM79149.1
KEGG: tbo:Thebr_0723 hypothetical protein.
   
 
 0.705
AEM78584.1
KEGG: tbo:Thebr_1044 preprotein translocase subunit YajC; TIGRFAM: YajC; PFAM: YajC.
   
  
 0.449
AEM78232.1
PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase, type II, C-terminal; KEGG: tmt:Tmath_0724 mannose-1-phosphate guanylyltransferase.
       0.434
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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