STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78245.1KEGG: tit:Thit_0658 hypothetical protein. (540 aa)    
Predicted Functional Partners:
AEM78246.1
PFAM: Outer membrane protein, OmpA/MotB, C-terminal; KEGG: tit:Thit_0659 OmpA/MotB domain protein.
 
   0.976
AEM78248.1
Manually curated; PFAM: SNF2-related; KEGG: tit:Thit_0661 SNF2-related protein; SMART: DEAD-like helicase, N-terminal.
 
 
 0.925
AEM78247.1
KEGG: tit:Thit_0660 hypothetical protein.
       0.799
AEM79154.1
KEGG: thx:Thet_1694 hypothetical protein.
   
 0.765
AEM79826.1
PFAM: Copper amine oxidase-like, N-terminal; KEGG: slp:Slip_1153 copper amine oxidase domain protein.
   
 0.749
AEM78020.1
PFAM: Anti-sigma-28 factor, FlgM; KEGG: tbo:Thebr_1831 anti-sigma-28 factor FlgM family protein.
  
 
 0.733
AEM78833.1
Hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
   
 0.704
AEM78744.1
TIGRFAM: Sporulation stage V, protein K; PFAM: ATPase, AAA-type, core; KEGG: tbo:Thebr_1211 stage V sporulation protein K; SMART: ATPase, AAA+ type, core.
  
 
 0.696
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 
 0.682
pcp
Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
   
   0.682
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.