| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEM77643.1 | htpX | Thewi_0133 | Thewi_0827 | AAA ATPase central domain protein; KEGG: tbo:Thebr_2172 vesicle-fusing ATPase; PFAM: ATPase, AAA-type, core; Peptidase M41; SMART: ATPase, AAA+ type, core. | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | 0.516 |
| AEM78257.1 | AEM78259.1 | Thewi_0826 | Thewi_0828 | KEGG: thx:Thet_0673 hypothetical protein. | LemA family protein; PFAM: LemA; KEGG: tbo:Thebr_1614 LemA family protein. | 0.650 |
| AEM78257.1 | htpX | Thewi_0826 | Thewi_0827 | KEGG: thx:Thet_0673 hypothetical protein. | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | 0.672 |
| AEM78257.1 | secY | Thewi_0826 | Thewi_2236 | KEGG: thx:Thet_0673 hypothetical protein. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.724 |
| AEM78259.1 | AEM78257.1 | Thewi_0828 | Thewi_0826 | LemA family protein; PFAM: LemA; KEGG: tbo:Thebr_1614 LemA family protein. | KEGG: thx:Thet_0673 hypothetical protein. | 0.650 |
| AEM78259.1 | htpX | Thewi_0828 | Thewi_0827 | LemA family protein; PFAM: LemA; KEGG: tbo:Thebr_1614 LemA family protein. | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | 0.864 |
| AEM79637.1 | grpE | Thewi_2289 | Thewi_1042 | KEGG: tbo:Thebr_0352 ATPase AAA-2 domain-containing protein; PFAM: ATPase associated with various cellular activities, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; UvrB/UvrC protein; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; Belongs to the ClpA/ClpB family. | Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.906 |
| AEM79637.1 | htpX | Thewi_2289 | Thewi_0827 | KEGG: tbo:Thebr_0352 ATPase AAA-2 domain-containing protein; PFAM: ATPase associated with various cellular activities, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; UvrB/UvrC protein; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; Belongs to the ClpA/ClpB family. | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | 0.429 |
| ftsH | htpX | Thewi_1995 | Thewi_0827 | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | 0.516 |
| ftsH-2 | htpX | Thewi_2334 | Thewi_0827 | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | 0.516 |
| grpE | AEM79637.1 | Thewi_1042 | Thewi_2289 | Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | KEGG: tbo:Thebr_0352 ATPase AAA-2 domain-containing protein; PFAM: ATPase associated with various cellular activities, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; UvrB/UvrC protein; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; Belongs to the ClpA/ClpB family. | 0.906 |
| grpE | htpX | Thewi_1042 | Thewi_0827 | Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | 0.455 |
| grpE | ribBA | Thewi_1042 | Thewi_0023 | Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.457 |
| htpX | AEM77643.1 | Thewi_0827 | Thewi_0133 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | AAA ATPase central domain protein; KEGG: tbo:Thebr_2172 vesicle-fusing ATPase; PFAM: ATPase, AAA-type, core; Peptidase M41; SMART: ATPase, AAA+ type, core. | 0.516 |
| htpX | AEM78257.1 | Thewi_0827 | Thewi_0826 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | KEGG: thx:Thet_0673 hypothetical protein. | 0.672 |
| htpX | AEM78259.1 | Thewi_0827 | Thewi_0828 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | LemA family protein; PFAM: LemA; KEGG: tbo:Thebr_1614 LemA family protein. | 0.864 |
| htpX | AEM79637.1 | Thewi_0827 | Thewi_2289 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | KEGG: tbo:Thebr_0352 ATPase AAA-2 domain-containing protein; PFAM: ATPase associated with various cellular activities, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; UvrB/UvrC protein; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; Belongs to the ClpA/ClpB family. | 0.429 |
| htpX | ftsH | Thewi_0827 | Thewi_1995 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.516 |
| htpX | ftsH-2 | Thewi_0827 | Thewi_2334 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.516 |
| htpX | grpE | Thewi_0827 | Thewi_1042 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1615 peptidase M48 Ste24p; Belongs to the peptidase M48B family. | Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.455 |
