Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
AEM78271.1KEGG: tbo:Thebr_1648 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP02678; PFAM: Conserved hypothetical protein CHP02678. (383 aa)    
Predicted Functional Partners:
AEM78270.1
KEGG: thx:Thet_0686 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP02677; PFAM: Conserved hypothetical protein CHP02677.
 
 
   0.988
AEM78272.1
TIGRFAM: Conserved hypothetical protein CHP02680; KEGG: tit:Thit_0689 chromosome segregation ATPase-like protein.
 
 
   0.988
AEM78273.1
Hypothetical protein; Manually curated.
 
     0.958
AEM78274.1
PFAM: Nucleotidyltransferase; KEGG: tbo:Thebr_1599 DNA polymerase beta domain-containing protein region.
       0.641
AEM77963.1
Hypothetical protein; Manually curated.
   
   0.627
AEM79741.1
Hypothetical protein; KEGG: tbo:Thebr_2254 peptidoglycan-binding domain 1 protein.
   
   0.627
AEM78275.1
PFAM: Protein of unknown function DUF86; KEGG: tbo:Thebr_1598 hypothetical protein.
 
     0.596
AEM78269.1
PFAM: 4-oxalocrotonate tautomerase; KEGG: tmt:Tmath_0739 4-oxalocrotonate tautomerase.
 
     0.569
AEM78267.1
PFAM: Uncharacterised protein family UPF0150; KEGG: tmt:Tmath_0737 protein of unknown function UPF0150.
 
     0.561
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
   
   0.558
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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