STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pdxTGlutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (194 aa)    
Predicted Functional Partners:
pdxS
Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
 0.999
AEM79134.1
PFAM: Transaldolase; KEGG: tit:Thit_1582 transaldolase.
    
  0.808
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
  0.808
AEM77666.1
Sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; Protein-tyrosine phosphatase, low molecular weight; KEGG: tit:Thit_0129 sugar-phosphate isomerase, RpiB/LacA/LacB family; SMART: Protein-tyrosine phosphatase, low molecular weight.
     
  0.800
AEM77804.1
Transketolase domain-containing protein; PFAM: Transketolase, N-terminal; KEGG: tbo:Thebr_0504 transketolase domain-containing protein.
     
  0.800
AEM77805.1
Transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: thx:Thet_1947 transketolase central region.
     
  0.800
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
     
  0.800
AEM78289.1
PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; KEGG: tbo:Thebr_1593 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II.
     
  0.800
AEM79131.1
KEGG: tit:Thit_1579 sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase.
     
  0.800
AEM79132.1
Transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: thx:Thet_1012 transketolase domain-containing protein.
     
  0.800
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.