STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78284.1DNA mismatch repair protein MutS domain protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (493 aa)    
Predicted Functional Partners:
AEM78283.1
KEGG: tte:TTE0724 hypothetical protein.
 
     0.958
AEM78285.1
PFAM: D-Lysine 5,6-aminomutase alpha subunit; KEGG: tte:TTE0726 D-lysine 5,6-aminomutase alpha subunit.
 
    0.947
AEM78286.1
Cobalamin B12-binding domain protein; PFAM: Cobalamin (vitamin B12)-binding; KEGG: tte:TTE0727 D-lysine 5,6-aminomutase beta subunit.
 
     0.946
AEM78281.1
KEGG: tte:TTE0722 hypothetical protein.
 
  
 0.941
mutL
ATP-binding region ATPase domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
 0.932
AEM78279.1
KEGG: tte:TTE0718 acyl-CoA hydrolase.
 
    0.899
AEM78280.1
PFAM: Protein of unknown function DUF849, prokaryotic; KEGG: tte:TTE0719 hypothetical protein.
 
     0.887
AEM78282.1
Lysine-2,3-aminomutase; KEGG: tte:TTE0723 lysine 2,3-aminomutase; TIGRFAM: lysine-2,3-aminomutase; Protein of unknown function DUF160; PFAM: Radical SAM.
 
     0.880
polA
5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.831
AEM77518.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.793
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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