Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEM78301.1PFAM: Protein of unknown function DUF458, RNase H-like; KEGG: tbo:Thebr_1580 hypothetical protein. (162 aa)    
Predicted Functional Partners:
AEM77642.1
KEGG: tbo:Thebr_2173 hypothetical protein.
  
     0.636
AEM78461.1
PFAM: Membrane protein of unknown function; KEGG: tbo:Thebr_1438 hypothetical protein.
  
     0.598
amj
Hypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
 
     0.581
AEM78302.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ttm:Tthe_1030 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
       0.504
AEM79880.1
KEGG: tbo:Thebr_0192 hypothetical protein.
 
     0.432
AEM78987.1
PFAM: Protein of unknown function DUF1614; KEGG: tbo:Thebr_0854 hypothetical protein.
  
     0.418
AEM77845.1
PFAM: Branched-chain amino acid transport; KEGG: tit:Thit_0286 branched-chain amino acid transport.
  
     0.404
AEM77633.1
PFAM: 3D; G5; Protein of unknown function DUF348; KEGG: tbo:Thebr_2182 3D domain-containing protein.
       0.402
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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