Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78309.1PFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: thx:Thet_0715 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase. (252 aa)    
Predicted Functional Partners:
AEM78308.1
Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1576 PP-loop domain-containing protein.
 
  
 0.993
larC
Protein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.984
AEM77748.1
PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; KEGG: thx:Thet_0230 cobalamin (vitamin B12) biosynthesis CbiM protein.
 
    0.805
AEM77746.1
KEGG: thx:Thet_0228 cobalt ABC transporter inner membrane subunit CbiQ; TIGRFAM: Cobalt ABC transporter CbiQ, permease subunit; PFAM: Cobalt transport protein.
 
    0.610
AEM77747.1
KEGG: tit:Thit_0211 hypothetical protein.
  
    0.514
AEM78307.1
Methyl-accepting chemotaxis sensory transducer with Cache sensor; KEGG: tte:TTE0759 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain.
       0.500
AEM80012.1
KEGG: tmt:Tmath_2258 transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SMART: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp.
  
  
 0.420
AEM78306.1
KEGG: thx:Thet_0713 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.403
cinA
KEGG: tbo:Thebr_1221 competence/damage-inducible protein CinA; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; Belongs to the CinA family.
       0.400
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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