Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEM78314.1KEGG: tbo:Thebr_1569 hypothetical protein. (185 aa)    
Predicted Functional Partners:
AEM79102.1
PFAM: Iron dependent repressor; KEGG: tbo:Thebr_0741 iron dependent repressor.
  
     0.590
AEM77827.1
KEGG: thx:Thet_0286 aminopeptidase-like protein.
  
     0.523
AEM79058.1
PFAM: Major facilitator superfamily MFS-1; KEGG: tbo:Thebr_0788 major facilitator superfamily protein.
  
     0.523
AEM78702.1
KEGG: tbo:Thebr_1160 hypothetical protein.
  
     0.517
AEM79554.1
Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
  
     0.476
AEM78377.1
PFAM: Peptidase M4, propeptide, PepSY; S-layer homology region; KEGG: tit:Thit_0804 propeptide PepSY amd peptidase M4.
  
     0.466
AEM79038.1
KEGG: tbo:Thebr_0806 hypothetical protein.
  
   
 0.462
AEM78922.1
KEGG: tmt:Tmath_1409 copper amine oxidase domain protein; PFAM: Copper amine oxidase-like, N-terminal; Transglutaminase-like; SMART: Transglutaminase-like.
  
     0.454
AEM77680.1
S-layer domain-containing protein; PFAM: S-layer homology region; KEGG: tte:TTE0166 S-layer-like domain-containing protein.
  
     0.453
AEM78311.1
Manually curated; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; KEGG: tbo:Thebr_1572 ATP-binding region ATPase domain-containing protein; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain.
 
     0.451
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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