Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78315.1PFAM: BioY protein; KEGG: tbo:Thebr_1568 BioY protein. (182 aa)    
Predicted Functional Partners:
ecfT
ABC-type transporter, integral membrane subunit; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 0.976
ecfA-2
ABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.952
ecfA
ABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.951
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.838
AEM77746.1
KEGG: thx:Thet_0228 cobalt ABC transporter inner membrane subunit CbiQ; TIGRFAM: Cobalt ABC transporter CbiQ, permease subunit; PFAM: Cobalt transport protein.
  
 
 0.773
AEM77745.1
KEGG: tit:Thit_0209 ABC transporter related protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
   
 
 0.731
AEM79227.1
KEGG: thx:Thet_1782 radical SAM domain-containing protein; PFAM: Radical SAM; Biotin/thiamin synthesis-associated protein; SMART: Elongator protein 3/MiaB/NifB.
  
  
 0.622
AEM79694.1
PFAM: Protein of unknown function DUF1284; KEGG: tit:Thit_2067 protein of unknown function DUF1284.
 
    0.498
AEM78062.1
Hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
  
   
 0.489
AEM78316.1
PFAM: Protein of unknown function DUF151; KEGG: tit:Thit_0734 protein of unknown function DUF151.
       0.489
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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