Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78338.1Peptidase S8 and S53 subtilisin kexin sedolisin; Serine protease with a broad substrate specificity. (576 aa)    
Predicted Functional Partners:
AEM78336.1
PFAM: Bacterial extracellular solute-binding, family 1; KEGG: tbo:Thebr_1549 family 1 extracellular solute-binding protein.
  
     0.506
AEM78410.1
KEGG: tbo:Thebr_1490 hypothetical protein.
  
     0.495
AEM77963.1
Hypothetical protein; Manually curated.
  
 
 0.470
AEM78270.1
KEGG: thx:Thet_0686 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP02677; PFAM: Conserved hypothetical protein CHP02677.
  
 
 0.470
AEM79741.1
Hypothetical protein; KEGG: tbo:Thebr_2254 peptidoglycan-binding domain 1 protein.
  
 
 0.470
AEM78341.1
PFAM: Mur ligase, central; KEGG: tit:Thit_0772 Mur ligase middle domain-containing protein.
  
     0.438
AEM78875.1
KEGG: tbo:Thebr_1342 serine/threonine-protein kinase-like domain-containing protein; PFAM: Serine/threonine-protein kinase-like domain; PASTA; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, subgroup, catalytic domain; PASTA.
 
 
 
 0.414
AEM77637.1
S-layer domain-containing protein; PFAM: S-layer homology region; KEGG: tit:Thit_0105 S-layer domain protein.
 
    0.410
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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