Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78341.1PFAM: Mur ligase, central; KEGG: tit:Thit_0772 Mur ligase middle domain-containing protein. (180 aa)    
Predicted Functional Partners:
AEM77523.1
PFAM: CobB/CobQ-like glutamine amidotransferase; KEGG: tbo:Thebr_0007 CobB/CobQ domain-containing protein glutamine amidotransferase.
  
 
 0.754
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
 
 0.747
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
 
 0.728
AEM77635.1
KEGG: tbo:Thebr_2180 hypothetical protein.
  
     0.721
AEM79437.1
KEGG: tbo:Thebr_0498 outer membrane lipoprotein-sorting protein-like protein.
 
     0.667
AEM78585.1
KEGG: tmt:Tmath_1069 hypothetical protein.
  
     0.635
AEM79885.1
KEGG: tbo:Thebr_0187 spore germination protein; TIGRFAM: Spore germination GerAB; PFAM: Spore germination GerAB.
  
    0.633
AEM79651.1
KEGG: thx:Thet_2096 hypothetical protein.
  
 
   0.629
AEM78340.1
KEGG: tbo:Thebr_1544 cell wall hydrolase SleB; PFAM: Cell wall hydrolase, SleB; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup.
 
   
 0.619
AEM78342.1
PFAM: Primosome PriB/single-strand DNA-binding; KEGG: thx:Thet_0747 single-strand-binding protein/primosomal replication protein N.
 
   
 0.619
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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