Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hutHTIGRFAM: Histidine ammonia-lyase; HAMAP: Histidine ammonia-lyase; KEGG: tbo:Thebr_1523 histidine ammonia-lyase; PFAM: Phenylalanine/histidine ammonia-lyase. (508 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.999
hutI
TIGRFAM: Imidazolonepropionase; HAMAP: Imidazolonepropionase; KEGG: tbo:Thebr_1883 imidazolonepropionase; PFAM: Amidohydrolase 1.
 
  
 0.991
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.925
AEM78058.1
PFAM: Amidohydrolase 1; KEGG: tbo:Thebr_1795 amidohydrolase.
  
  
 0.821
AEM78362.1
KEGG: thx:Thet_0766 hypothetical protein.
       0.765
AEM78712.1
Agmatinase; KEGG: tbo:Thebr_1172 agmatinase; TIGRFAM: Putative agmatinase; PFAM: Ureohydrolase; Belongs to the arginase family.
  
  
 0.756
AEM77969.1
KEGG: thx:Thet_0437 glutamate formiminotransferase; TIGRFAM: Formiminotransferase; PFAM: Formiminotransferase, N-terminal; Formiminotransferase, C-terminal.
 
    0.638
AEM77978.1
Formiminotransferase-cyclodeaminase; PFAM: Cyclodeaminase/cyclohydrolase; KEGG: thx:Thet_0447 formiminotransferase-cyclodeaminase.
 
  
 0.621
gcvPB
Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
   
  
 0.453
AEM78360.1
KEGG: tbo:Thebr_1524 hypothetical protein.
       0.448
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.