Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEM78386.1Two component transcriptional regulator, LytTR family; KEGG: tte:TTE0870 response regulators of cell autolysis; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region. (255 aa)    
Predicted Functional Partners:
AEM78387.1
KEGG: tte:TTE0871 regulator of cell autolysis; PFAM: Signal transduction histidine kinase, internal region; Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like.
 
 0.997
AEM77976.1
KEGG: thx:Thet_0445 multi-sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; Cache; ATP-binding region, ATPase-like; SMART: HAMP linker domain.
 
  
 0.785
AEM77786.1
KEGG: thx:Thet_0264 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SMART: HAMP linker domain; ATP-binding region, ATPase-like.
 
  
 0.762
AEM78385.1
PFAM: Carbon starvation protein CstA; KEGG: tte:TTE0869 carbon starvation protein, membrane protein.
 
   
 0.668
AEM78388.1
KEGG: tmt:Tmath_0848 RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma factor 70, region 4 type 2.
 
  
 0.572
AEM78389.1
KEGG: tmt:Tmath_0849 putative transmembrane anti-sigma factor.
       0.504
AEM79712.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: tbo:Thebr_0292 EAL domain-containing protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted.
 
   
 0.476
AEM78384.1
KEGG: tte:TTE0868 hypothetical protein.
       0.463
polA
5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.424
AEM77965.1
KEGG: tbo:Thebr_1890 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
    0.411
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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