Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM78389.1KEGG: tmt:Tmath_0849 putative transmembrane anti-sigma factor. (382 aa)    
Predicted Functional Partners:
AEM78388.1
KEGG: tmt:Tmath_0848 RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma factor 70, region 4 type 2.
  
 
 0.913
polA
5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.738
AEM79690.1
RNA polymerase, sigma-24 subunit, ECF subfamily; Manually curated; TIGRFAM: RNA polymerase sigma-70; KEGG: tit:Thit_2063 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma factor 70, region 4 type 2.
 
 
 0.689
AEM79446.1
KEGG: thx:Thet_2281 RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2.
  
 
 0.635
AEM79827.1
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: ctc:CTC00608 RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70; PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.635
AEM79149.1
KEGG: tbo:Thebr_0723 hypothetical protein.
  
     0.634
AEM78920.1
KEGG: thx:Thet_1089 RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2.
  
 
 0.633
AEM79620.1
RNA polymerase, sigma-24 subunit, SigH, ECF subfamily; KEGG: tbo:Thebr_0367 RNA polymerase sigma-H factor; TIGRFAM: RNA polymerase sigma-H type; RNA polymerase sigma-70; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma factor 70, region 4 type 2.
  
 
 0.632
AEM79828.1
KEGG: ctc:CTC01785 hypothetical protein.
  
 
 0.632
AEM77826.1
KEGG: thx:Thet_0285 hypothetical protein.
 
   
 0.611
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.