AEM78396.1 protein (Thermoanaerobacter wiegelii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

AEM78396.1

KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal. (611 aa)

Predicted Functional Partners:

guaA

0.736

polA

0.619

rpsI

0.529

AEM78395.1

0.525

trmD

0.521

rpmI

0.520

tig

0.513

rplA

0.507

ychF

0.505

rimP

0.495

Your Current Organism:

Thermoanaerobacter wiegelii

NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEM78395.1	AEM78396.1	Thewi_0966	Thewi_0967	KEGG: tit:Thit_0817 NLP/P60 protein; PFAM: NLP/P60; SH3, type 3; SMART: Bacterial SH3-like region.	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	0.525
AEM78396.1	AEM78395.1	Thewi_0967	Thewi_0966	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	KEGG: tit:Thit_0817 NLP/P60 protein; PFAM: NLP/P60; SH3, type 3; SMART: Bacterial SH3-like region.	0.525
AEM78396.1	guaA	Thewi_0967	Thewi_0667	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.736
AEM78396.1	polA	Thewi_0967	Thewi_0961	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.619
AEM78396.1	rimP	Thewi_0967	Thewi_1353	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	Ribosome maturation factor rimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.	0.495
AEM78396.1	rplA	Thewi_0967	Thewi_2266	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.507
AEM78396.1	rpmI	Thewi_0967	Thewi_1654	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	TIGRFAM: Ribosomal protein L35; HAMAP: Ribosomal protein L35; KEGG: tbo:Thebr_0791 50S ribosomal protein L35; PFAM: Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.520
AEM78396.1	rpsI	Thewi_0967	Thewi_2220	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	PFAM: Ribosomal protein S9; KEGG: tbo:Thebr_0419 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.529
AEM78396.1	tig	Thewi_0967	Thewi_0739	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.513
AEM78396.1	trmD	Thewi_0967	Thewi_1413	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.	0.521
AEM78396.1	ychF	Thewi_0967	Thewi_1617	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	GTP-binding protein HSR1-related protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.505
guaA	AEM78396.1	Thewi_0667	Thewi_0967	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	0.736
guaA	polA	Thewi_0667	Thewi_0961	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.849
guaA	rplA	Thewi_0667	Thewi_2266	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.904
guaA	rpmI	Thewi_0667	Thewi_1654	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	TIGRFAM: Ribosomal protein L35; HAMAP: Ribosomal protein L35; KEGG: tbo:Thebr_0791 50S ribosomal protein L35; PFAM: Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.466
guaA	rpsI	Thewi_0667	Thewi_2220	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	PFAM: Ribosomal protein S9; KEGG: tbo:Thebr_0419 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.638
guaA	tig	Thewi_0667	Thewi_0739	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.649
guaA	trmD	Thewi_0667	Thewi_1413	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.	0.731
guaA	ychF	Thewi_0667	Thewi_1617	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	GTP-binding protein HSR1-related protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.689
polA	AEM78396.1	Thewi_0961	Thewi_0967	5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.	0.619

page 1 of 4

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About