STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78396.1KEGG: tbo:Thebr_1503 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal. (611 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.752
rplA
Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
    0.738
der
GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.661
AEM79799.1
TIGRFAM: Small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; KEGG: tit:Thit_2142 small GTP-binding protein; SMART: Ras small GTPase, Ras type.
  
  
 0.574
polA
5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.554
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.548
ychF
GTP-binding protein HSR1-related protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.533
AEM78395.1
KEGG: tit:Thit_0817 NLP/P60 protein; PFAM: NLP/P60; SH3, type 3; SMART: Bacterial SH3-like region.
       0.528
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
    0.523
rpsI
PFAM: Ribosomal protein S9; KEGG: tbo:Thebr_0419 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
    0.518
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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