Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78413.1KEGG: tbo:Thebr_1487 MreB/Mrl family cell shape determining protein; TIGRFAM: Cell shape determining protein MreB/Mrl; PFAM: Cell shape determining protein MreB/Mrl. (339 aa)    
Predicted Functional Partners:
AEM78414.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.992
AEM78416.1
KEGG: tbo:Thebr_1484 penicillin-binding protein 2; manually curated; PFAM: Penicillin-binding protein, dimerisation domain.
 
 
 
 0.963
AEM78415.1
TIGRFAM: Cell shape-determining protein MreD; KEGG: tbo:Thebr_1485 rod shape-determining protein MreD.
  
  
 0.886
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 
 0.886
AEM79186.1
KEGG: thx:Thet_1724 hypothetical protein.
 
 
 0.884
AEM78412.1
KEGG: tpd:Teth39_1453 DNA repair protein RadC; TIGRFAM: DNA repair, RadC-like; PFAM: DNA repair, RadC-like; Belongs to the UPF0758 family.
  
  
 0.835
AEM78411.1
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.802
minC
Septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
  
  
 0.775
AEM78418.1
KEGG: tmt:Tmath_0878 septum site-determining protein MinD; TIGRFAM: Septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase.
  
 
 0.744
AEM78410.1
KEGG: tbo:Thebr_1490 hypothetical protein.
       0.701
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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