Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78415.1TIGRFAM: Cell shape-determining protein MreD; KEGG: tbo:Thebr_1485 rod shape-determining protein MreD. (172 aa)    
Predicted Functional Partners:
AEM78414.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.992
minC
Septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
 
  
 0.947
AEM78413.1
KEGG: tbo:Thebr_1487 MreB/Mrl family cell shape determining protein; TIGRFAM: Cell shape determining protein MreB/Mrl; PFAM: Cell shape determining protein MreB/Mrl.
  
  
 0.886
AEM78418.1
KEGG: tmt:Tmath_0878 septum site-determining protein MinD; TIGRFAM: Septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase.
  
  
 0.875
AEM78416.1
KEGG: tbo:Thebr_1484 penicillin-binding protein 2; manually curated; PFAM: Penicillin-binding protein, dimerisation domain.
  
  
 0.864
AEM78410.1
KEGG: tbo:Thebr_1490 hypothetical protein.
 
     0.824
AEM78412.1
KEGG: tpd:Teth39_1453 DNA repair protein RadC; TIGRFAM: DNA repair, RadC-like; PFAM: DNA repair, RadC-like; Belongs to the UPF0758 family.
  
  
 0.801
AEM78411.1
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.790
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
 
     0.669
AEM78796.1
PFAM: Type IV pilus assembly PilZ; KEGG: thx:Thet_1230 type IV pilus assembly PilZ.
  
    0.664
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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