STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
minECell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (91 aa)    
Predicted Functional Partners:
AEM78418.1
KEGG: tmt:Tmath_0878 septum site-determining protein MinD; TIGRFAM: Septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase.
 
 
 0.998
minC
Septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
 
  
 0.941
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
     
 0.712
AEM78415.1
TIGRFAM: Cell shape-determining protein MreD; KEGG: tbo:Thebr_1485 rod shape-determining protein MreD.
 
     0.689
AEM78426.1
KEGG: tbo:Thebr_1474 ribonuclease, Rne/Rng family; TIGRFAM: Ribonuclease E/G; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain.
  
    0.674
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
       0.640
AEM78416.1
KEGG: tbo:Thebr_1484 penicillin-binding protein 2; manually curated; PFAM: Penicillin-binding protein, dimerisation domain.
  
  
 0.637
AEM77543.1
KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region.
   
    0.629
AEM78413.1
KEGG: tbo:Thebr_1487 MreB/Mrl family cell shape determining protein; TIGRFAM: Cell shape determining protein MreB/Mrl; PFAM: Cell shape determining protein MreB/Mrl.
  
  
 0.622
AEM78414.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
       0.597
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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