Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78424.1KEGG: tbo:Thebr_1476 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (617 aa)    
Predicted Functional Partners:
AEM78425.1
PFAM: Protein of unknown function DUF2344; KEGG: thx:Thet_0813 hypothetical protein.
    0.996
AEM78426.1
KEGG: tbo:Thebr_1474 ribonuclease, Rne/Rng family; TIGRFAM: Ribonuclease E/G; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain.
       0.839
AEM78423.1
PFAM: Peptidase M50; KEGG: tbo:Thebr_1477 peptidase M50.
       0.794
AEM78422.1
PFAM: Peptidase M23; KEGG: tbo:Thebr_1478 peptidase M23.
       0.744
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
       0.648
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
    0.576
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
       0.534
AEM78418.1
KEGG: tmt:Tmath_0878 septum site-determining protein MinD; TIGRFAM: Septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase.
       0.513
AEM78432.1
PFAM: Protein of unknown function DUF464; KEGG: tbo:Thebr_1469 hypothetical protein.
  
    0.489
AEM78414.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
     0.488
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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