Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM78430.1KEGG: tpd:Teth39_1436 hypothetical protein. (123 aa)    
Predicted Functional Partners:
AEM78429.1
Protein of unknown function UPF0236; KEGG: tte:TTE2708 hypothetical protein; manually curated; PFAM: Uncharacterised protein family UPF0236.
 
    0.638
AEM78437.1
Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; HDIG; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: tit:Thit_0857 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD region.
  
    0.599
AEM77599.1
SirA-like domain-containing protein; PFAM: SirA-like; KEGG: tte:TTE0081 transcriptional regulator; Belongs to the sulfur carrier protein TusA family.
  
     0.538
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
       0.505
rpmA
TIGRFAM: Ribosomal protein L27; HAMAP: Ribosomal protein L27; KEGG: tbo:Thebr_1468 50S ribosomal protein L27; PFAM: Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
       0.505
AEM78432.1
PFAM: Protein of unknown function DUF464; KEGG: tbo:Thebr_1469 hypothetical protein.
       0.503
AEM77638.1
KEGG: tmt:Tmath_0163 hypothetical protein.
 
     0.500
AEM77637.1
S-layer domain-containing protein; PFAM: S-layer homology region; KEGG: tit:Thit_0105 S-layer domain protein.
  
     0.447
sigI
RNA polymerase sigma-I factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily.
  
     0.446
obg
GTP1/OBG sub domain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.424
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (10%) [HD]